Current Issue February 2012, Vol. 52, No. 2

Issue Highlights

Local control in cardiac E–C coupling
February 2012(Vol. 52 | No. 2 | Pages 298-303)
M.B. Cannell, Cherrie H.T. Kong

Dynamic local changes in sarcoplasmic reticulum calcium: Physiological and pathophysiological roles
February 2012(Vol. 52 | No. 2 | Pages 304-311)
Eric A. Sobie, W.J. Lederer

Calmodulin binding proteins provide domains of local Ca2+ signaling in cardiac myocytes
February 2012(Vol. 52 | No. 2 | Pages 312-316)
Jeffrey J. Saucerman, Donald M. Bers

Une cellule type?
06 February 2012
Leighton T. Izu, Ye Chen-Izu
The function is called the Gaussian distribution or normal distribution with about equal frequency. We have used the two names interchangeably. However, these names reflect the two fundamentally diffe...
MyD88 mediated inflammatory signaling leads to CaMKII oxidation, cardiac hypertrophy and death after myocardial infarction
06 February 2012
Madhu V. Singh, Swaminathan, E.D. Luczak, W. Kutschke, R.M. Weiss, M.E. Anderson
Abstract: The toll-like receptors (TLR) and myocardial infarction (MI) promote NF-κB-dependent inflammatory transcription and oxidative injury in myocardium. The multifunctional Ca2+/calmodulin-depend...
Cancer therapy modulates VEGF signaling and viability in adult rat cardiac microvascular endothelial cells and cardiomyocytes
06 February 2012
Manuel Chiusa, Sara-Lynn Hool, Petra Truetsch, Siamak Djafarzadeh, Stephan M. Jakob, Franziska Seifriz, Stefan J. Scherer, Thomas M. Suter, Christian Zuppinger, Stephan Zbinden
Abstract: This work was motivated by the incomplete characterization of the role of vascular endothelial growth factor-A (VEGF-A) in the stressed heart in consideration of upcoming cancer treatment op...
Shear stress-induced activation of Tie2-dependent signaling pathway enhances reendothelialization capacity of early endothelial progenitor cells
03 February 2012
Zhen Yang, Wen-Hao Xia, Yuan-Yuan Zhang, Shi-Yue Xu, Xing Liu, Xiao-Yu Zhang, Bing-Bo Yu, Yan-Xia Qiu, Jun Tao
Abstract: Although endothelial progenitor cells (EPCs) play a pivotal role in the endothelial repair following arterial injury and shear stress has a beneficial effect on EPCs, however, the molecular ...
Regulation of microRNA Expression in the Heart by the ATF6 Branch of the ER Stress Response
03 February 2012
Peter J. Belmont, Wenqiong J. Chen, Donna J. Thuerauf, Christopher C. Glembotski
Abstract: A nodal regulator of endoplasmic reticulum stress is the transcription factor, ATF6, which is activated by ischemia and protects the heart from ischemic damage, in vivo. To explore mechanism...

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The Journal of Molecular and Cellular Cardiology is published for the International Society for Heart Research by Elsevier.

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About JMCC

The Journal of Molecular and Cellular Cardiology publishes work advancing knowledge of the mechanisms responsible for both normal and diseased cardiovascular function. To this end papers are published in all relevant areas. These include (but are not limited to): structural biology; genetics; proteomics; morphology; stem cells; molecular biology; metabolism; biophysics; electrophysiology; pharmacology and physiology. Papers are encouraged with both basic and translational approaches. The journal is directed not only to basic scientists but also to clinical cardiologists who wish to follow the rapidly advancing frontiers of basic knowledge of the heart and circulation.

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