Journal of Molecular and Cellular Cardiology
Volume 52, Issue 3 , Pages 753-760 , March 2012

Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress

  • Xu Wang

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
    • Whitaker Cardiovascular Institute and Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
  • ,
  • Lei Cui

      Affiliations

    • Whitaker Cardiovascular Institute and Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
  • ,
  • Jacob Joseph

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
    • Department of Medicine, VA Boston Healthcare System, West Roxbury, MA 02132, USA
  • ,
  • Bingbing Jiang

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
  • ,
  • David Pimental

      Affiliations

    • Whitaker Cardiovascular Institute and Evans Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA
  • ,
  • Diane E. Handy

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
  • ,
  • Ronglih Liao

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
  • ,
  • Joseph Loscalzo

      Affiliations

    • Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA
    • Corresponding Author InformationCorresponding author at: Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Tel.: +1 617 732 6340; fax: +1 617 732 6439.

Received 14 October 2011 ,Revised 13 December 2011 ,Accepted 20 December 2011.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.

PII: S0022-2828(11)00516-5

doi: 10.1016/j.yjmcc.2011.12.009

Journal of Molecular and Cellular Cardiology
Volume 52, Issue 3 , Pages 753-760 , March 2012