Journal of Molecular and Cellular Cardiology
Volume 52, Issue 3 , Pages 638-649 , March 2012

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction

  • Eun Young Kim

      Affiliations

    • Program in Genes and Development, The University of Texas Health Science Center at Houston, USA
    • Center for Stem Cell Engineering, Department of Basic Research Laboratories, Texas Heart Institute at St. Luke's Episcopal Hospital, 6770 Bertner Avenue, MC 2-255, Houston, TX 77030, USA
  • ,
  • Li Chen

      Affiliations

    • Center for Stem Cell Engineering, Department of Basic Research Laboratories, Texas Heart Institute at St. Luke's Episcopal Hospital, 6770 Bertner Avenue, MC 2-255, Houston, TX 77030, USA
  • ,
  • Yanlin Ma

      Affiliations

    • Center for Molecular Development and Disease, Institute of Biosciences and Technology, Texas A&M Health Science Center, 2121 W. Holcombe Blvd., Houston, TX 77030, USA
  • ,
  • Wei Yu

      Affiliations

    • Department of Biochemistry and Molecular Biology, University of Houston, Houston, TX 77204, USA
  • ,
  • Jiang Chang

      Affiliations

    • Center for Molecular Development and Disease, Institute of Biosciences and Technology, Texas A&M Health Science Center, 2121 W. Holcombe Blvd., Houston, TX 77030, USA
  • ,
  • Ivan P. Moskowitz

      Affiliations

    • Department of Pediatrics and Pathology, The University of Chicago, 5841 S. Maryland Avenue, MC 1059, Chicago, IL 60637, USA
  • ,
  • Jun Wang

      Affiliations

    • Center for Stem Cell Engineering, Department of Basic Research Laboratories, Texas Heart Institute at St. Luke's Episcopal Hospital, 6770 Bertner Avenue, MC 2-255, Houston, TX 77030, USA
    • Corresponding Author InformationCorresponding author at: Texas Heart Institute. Tel.: +1 832 355 9542.

Received 29 April 2011 ,Revised 16 November 2011 ,Accepted 18 November 2011.

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PII: S0022-2828(11)00477-9

doi: 10.1016/j.yjmcc.2011.11.011

Journal of Molecular and Cellular Cardiology
Volume 52, Issue 3 , Pages 638-649 , March 2012