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Journal of Molecular and Cellular Cardiology
Volume 52, Issue 2
, Pages 304-311
, February 2012
Dynamic local changes in sarcoplasmic reticulum calcium: Physiological and pathophysiological roles
References
- Cannell MB, Kong CHT. Local control in cardiac E-C coupling. J Mol Cell Cardiol 2012;52:298-303.
- Three-dimensional distribution of ryanodine receptor clusters in cardiac myocytes. Biophys J. 2006;91:1–13
- . Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes. Proc Natl Acad Sci USA. 2009;106:22275–22280
- . Shape, size, and distribution of Ca2+ release units and couplons in skeletal and cardiac muscles. Biophys J. 1999;77:1528–1539
- . Calcium sparks: elementary events underlying excitation–contraction coupling in heart muscle. Science. 1993;262:740–744
- . The control of calcium release in heart muscle. Science. 1995;268:1045–1049
- . Local calcium transients triggered by single L-type calcium channel currents in cardiac cells. Science. 1995;268:1042–1045
- . Allosteric activation of Na+-Ca2+ exchange by L-type Ca2+ current augments the trigger flux for SR Ca2+ release in ventricular myocytes. Biophys J. 2008;94:L54–L56
- . Na+ currents are required for efficient excitation–contraction coupling in rabbit ventricular myocytes: a possible contribution of neuronal Na+ channels. J Physiol. 2010;588:4249–4260
- . Calcium sparks and [Ca2+]i waves in cardiac myocytes. Am J Physiol. 1996;270:C148–C159
- . Spark-induced sparks as a mechanism of intracellular calcium alternans in cardiac myocytes. Circ Res. 2010;106:1582–1591
- Remodeling of T-tubules and reduced synchrony of Ca2+ release in myocytes from chronically ischemic myocardium. Circ Res. 2008;102:338–346
- Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes. Cardiovasc Res. 2004;62:63–73
- T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. J Physiol (Lond). 2006;574:519–533
- . Orphaned ryanodine receptors in the failing heart. Proc Natl Acad Sci USA. 2006;103:4305–4310
- . Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction. J Mol Cell Cardiol. 2011;50:390–400
- . Local calcium gradients during excitation-contraction coupling and alternans in atrial myocytes. J Physiol. 2003;546:19–31
- . Calcium signalling during excitation-contraction coupling in mammalian atrial myocytes. J Cell Sci. 2006;119:3915–3925
- . Location of the initiation site of calcium transients and sparks in rabbit heart Purkinje cells. J Physiol. 2001;531:301–314
- . Complex and rate-dependent beat-to-beat variations in Ca2+ transients of canine Purkinje cells. J Mol Cell Cardiol. 2011;50:662–669
- . Potentiation of fractional sarcoplasmic reticulum calcium release by total and free intra-sarcoplasmic reticulum calcium concentration. Biophys J. 2000;78:334–343
- . Modulation of CICR has no maintained effect on systolic Ca2+: simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca2+ fluxes in rat ventricular myocytes. J Physiol. 2000;522(Pt 2):259–270
- . Measurement of sarcoplasmic reticulum Ca2+ content and sarcolemmal Ca2+ fluxes in isolated rat ventricular myocytes during spontaneous Ca2+ release. J Physiol (Lond). 1997;501(Pt 1):3–16
- . What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis?. J Mol Cell Cardiol. 2009;46:474–481
- . Quantitative assessment of the SR Ca2+ leak-load relationship. Circ Res. 2002;91:594–600
- . Measurement and modeling of Ca2+ waves in isolated rabbit ventricular cardiomyocytes. Biophys J. 2007;93:2581–2595
- . Sarcoplasmic reticulum calcium content fluctuation is the key to cardiac alternans. Circ Res. 2004;94:650–656
- . Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak. Biophys J. 2008;95:3100–3110
- . Cardiac alternans do not rely on diastolic sarcoplasmic reticulum calcium content fluctuations. Circ Res. 2006;99:740–748
- . Calsequestrin-mediated mechanism for cellular calcium transient alternans. Biophys J. 2008;95:3767–3789
- . Alternans and arrhythmias: from cell to heart. Circ Res. 2011;108:98–112
- . Cellular mechanisms of arrhythmogenic cardiac alternans. Prog Biophys Mol Biol. 2008;97:332–347
- . Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle?. Cell Calcium. 2004;35:591–601
- . Cardiac excitation–contraction coupling. Nature. 2002;415:198–205
- . Ca2+ release mechanisms, Ca2+ sparks, and local control of excitation–contraction coupling in normal heart muscle. Circ Res. 1999;85:770–776
- . Calcium signalling in cardiac muscle: refractoriness revealed by coherent activation. Nat Cell Biol. 1999;1:323–329
- . Fractional SR Ca release is regulated by trigger Ca and SR Ca content in cardiac myocytes. Am J Physiol. 1995;268:C1313–C1319
- . Evidence for Ca2+ activation and inactivation sites on the luminal side of the cardiac ryanodine receptor complex. Circ Res. 2000;87:201–206
- . Regulation of the cardiac ryanodine receptor channel by luminal Ca2+ involves luminal Ca2+ sensing sites. Biophys J. 1998;75:2801–2810
- . Termination of cardiac Ca2+ sparks: an investigative mathematical model of calcium-induced calcium release. Biophys J. 2002;83:59–78
- . Luminal Ca2+ controls termination and refractory behavior of Ca2+-induced Ca2+ release in cardiac myocytes. Circ Res. 2002;91:414–420
- . The use of the indicator fluo-5N to measure sarcoplasmic reticulum calcium in single muscle fibres of the cane toad. J Physiol. 2001;534:87–97
- . Ca2+ scraps. local depletions of free [Ca2+] in cardiac sarcoplasmic reticulum during contractions leave substantial Ca2+reserve. Circ Res. 2003;93:40–45
- . Ca2+ blinks: rapid nanoscopic store calcium signaling. Proc Natl Acad Sci USA. 2005;102:3099–3104
- . Calsequestrin determines the functional size and stability of cardiac intracellular calcium stores: Mechanism for hereditary arrhythmia. Proc Natl Acad Sci USA. 2003;100:11759–11764
- Abnormal interactions of calsequestrin with the ryanodine receptor calcium release channel complex linked to exercise-induced sudden cardiac death. Circ Res. 2006;98:1151–1158
- Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death. Biophys J. 2008;95:2037–2048
- Abnormal calcium signaling and sudden cardiac death associated with mutation of calsequestrin. Circ Res. 2004;94:471–477
- . Partial inhibition of sarcoplasmic reticulum Ca release evokes long-lasting Ca release events in ventricular myocytes: Role of luminal Ca in termination of Ca release. Biophys J. 2008;94:1867–1879
- . Termination of cardiac Ca2+ sparks: role of intra-SR [Ca2+], release flux, and intra-SR Ca2+ diffusion. Circ Res. 2008;103:e105–e115
- . Assessment of sarcoplasmic reticulum Ca2+ depletion during spontaneous Ca2+ waves in isolated permeabilized rabbit ventricular cardiomyocytes. Biophys J. 2009;96:2744–2754
- . Intra-sarcoplasmic reticulum Ca2+ oscillations are driven by dynamic regulation of ryanodine receptor function by luminal Ca2+ in cardiomyocytes. J Physiol. 2009;587:4863–4872
- . Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle. Circ Res. 2004;95:807–813
- . Local recovery of Ca2+ release in rat ventricular myocytes. J Physiol. 2005;565:441–447
- . Recovery of cardiac calcium release is controlled by sarcoplasmic reticulum refilling and ryanodine receptor sensitivity. Cardiovasc Res. 2011;91:598–605
- . Ca2+ stores regulate ryanodine receptor Ca2+ release channels via luminal and cytosolic Ca2+ sites. Biophys J. 2007;92:3541–3555
- Luminal Ca2+ regulation of single cardiac ryanodine receptors: insights provided by calsequestrin and its mutants. J Gen Physiol. 2008;131:325–334
- . The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium. Biophys J. 2004;86:2121–2128
- Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc Natl Acad Sci USA. 2009;106:7636–7641
- Protein protein interactions between triadin and calsequestrin are involved in modulation of sarcoplasmic reticulum calcium release in cardiac myocytes. J Physiol. 2007;583:71–80
- . Predicting local SR Ca2+ dynamics during Ca2+ wave propagation in ventricular myocytes. Biophys J. 2010;98:2515–2523
- . Ryanodine receptor arrays: not just a pretty pattern?. Trends Cell Biol. 2008;18:149–156
- . Coordinated control of cell Ca2+ loading and triggered release from the sarcoplasmic reticulum underlies the rapid inotropic response to increased L-type Ca2+ current. Circ Res. 2001;88:195–201
- . Excitation–contraction coupling and cardiac contractile force. Second ed.. Dordrecht: Kluwer Academic Publishers; 2001;
- . Unitary Ca2+ current through mammalian cardiac and amphibian skeletal muscle ryanodine receptor Channels under near-physiological ionic conditions. J Gen Physiol. 2003;122:407–417
- RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR). Proc Natl Acad Sci USA. 2004;101:13062–13067
- Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death. Circ Res. 2005;97:1173–1181
- . Subcellular Ca2+ signaling in the heart: the role of ryanodine receptor sensitivity. J Gen Physiol. 2010;136:135–142
- Variability in timing of spontaneous calcium release in the intact rat heart is determined by the time course of sarcoplasmic reticulum calcium load. Circ Res. 2010;107:1117–1126
- . Calcium sparks and excitation-contraction coupling in phospholamban- deficient mouse ventricular myocytes. J Physiol (Lond). 1997;503:21–29
- . Ca2+ diffusion and sarcoplasmic reticulum transport both contribute to [Ca2+]i decline during Ca2+ sparks in rat ventricular myocytes. J Physiol (Lond). 1996;496:575–581
- Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia. J Clin Invest. 2006;116:2510–2520
- Calsequestrin 2 (CASQ2) mutations increase expression of calreticulin and ryanodine receptors, causing catecholaminergic polymorphic ventricular tachycardia. J Clin Invest. 2007;117:1814–1823
- . Calsequestrin Determines Refractoriness Of Calcium Release From Sarcoplasmic Reticulum Of Cardiac Muscle. Biophys J. 2008;94:898A
- Unexpected structural and functional consequences of the R33Q homozygous mutation in cardiac calsequestrin: a complex arrhythmogenic cascade in a knock in mouse model. Circ Res. 2008;103:298–306
- . Calcium waves driven by “sensitization” wave-fronts. Cardiovasc Res. 2007;74:39–45
- . The role of luminal Ca2+ in the generation of Ca2+ waves in rat ventricular myocytes. J Physiol (Lond). 1999;518:173–186
- . Modeling calcium waves in cardiac myocytes: importance of calcium diffusion. Front Biosci. 2010;15:661–680
- . A bidomain threshold model of propagating calcium waves. J Math Biol. 2008;56:435–463
- . Ca2+-mobility in the sarcoplasmic reticulum of ventricular myocytes is low. Biophys J. 2008;95:1412–1427
- . Sarcoplasmic reticulum and nuclear envelope are one highly interconnected Ca2+ store throughout cardiac myocyte. Circ Res. 2006;99:283–291
- . Dynamic calcium movement inside cardiac sarcoplasmic reticulum during release. Circ Res. 2011;108:847–856
- . Polymorphism of Ca2+ sparks evoked from in-focus Ca2+ release units in cardiac myocytes. Biophys J. 2004;86:182–190
- . The quantal nature of Ca2+ sparks and in situ operation of the ryanodine receptor array in cardiac cells. Proc Natl Acad Sci USA. 2004;101:3979–3984
- . Time course of individual Ca2+ sparks in frog skeletal muscle recorded at high time resolution. J Gen Physiol. 1999;113:187–198
- . Calcium-dependent inactivation terminates calcium release in skeletal muscle of amphibians. J Gen Physiol. 2008;131:335–348
- . Quarky calcium release in the heart. Circ Res. 2011;108:210–218
- The Ca2+ leak paradox and rogue ryanodine receptors: SR Ca2+ efflux theory and practice. Prog Biophys Mol Biol. 2006;90:172–185
- Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum. PLoS Comput Biol. 2010;6:e1000972
- . Interplay of ryanodine receptor distribution and calcium dynamics. Biophys J. 2006;91:95–112
- . Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model. Biophys J. 2005;89:4096–4110
- . Role of CaMKII in RyR leak, EC coupling and action potential duration: a computational model. J Mol Cell Cardiol. 2010;49:617–624
- . Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophys J. 2006;90:77–91
- . Spontaneous Ca2+ sparks and Ca2+ homeostasis in a minimal model of permeabilized ventricular myocytes. Am J Physiol Heart Circ Physiol. 2010;299:H1996–H2008
- . Moment closure for local control models of calcium-induced calcium release in cardiac myocytes. Biophys J. 2008;95:1689–1703
- . Parameter sensitivity analysis in electrophysiological models using multivariable regression. Biophys J. 2009;96:1264–1274
- . A meta-analysis of cardiac electrophysiology computational models. Exp Physiol. 2009;94:486–495
- . Regression analysis for constraining free parameters in electrophysiological models of cardiac cells. PLoS Comput Biol. 2010;6:e1000914
- . Excitation-contraction coupling gain in ventricular myocytes: insights from a parsimonious model. J Physiol. 2009;587:1293–1299
PII: S0022-2828(11)00263-X
doi: 10.1016/j.yjmcc.2011.06.024
© 2011 Elsevier Ltd. All rights reserved.
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Journal of Molecular and Cellular Cardiology
Volume 52, Issue 2
, Pages 304-311
, February 2012
