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Journal of Molecular and Cellular Cardiology
Volume 50, Issue 5
, Pages 777-784
, May 2011
S100A1 gene therapy for heart failure: A novel strategy on the verge of clinical trials
References
- . Heart disease and stroke statistics — 2010 update. Circulation. 2010;121:e1–e170
- . Cardiac hypertrophy: the good, the bad, and the ugly. Annu Rev Physiol. 2003;65:45–79
- . Gene therapy in heart failure. Circ Res. 2008;102(12):1458–1470
- . Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol. 2008;70:23–49
- . Is depressed myocyte contractility centrally involved in heart failure?. Circ Res. 2003;92(4):350–358
- . Prospects for gene therapy for heart failure. Circ Res. 2000;86(6):616–621
- Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. J Card Fail. 2008;14(5):355–367
- S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapy. J Mol Cell Cardiol. 2009;47(4):445–455
- . S100A1: a novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevance. Am J Physiol Regul Integr Comp Physiol. 2007;293(2):R568–R577
- . S100A1: a regulator of striated muscle sarcoplasmic reticulum Ca2+ handling, sarcomeric, and mitochondrial function. J Biomed Biotechnol. 2010;178614
- . S100A1: a calcium-modulating inotropic prototype for future clinical heart failure therapy. Future Cardiol. 2007;3:5–11
- . S100A1: structure, function, and therapeutic potential. Curr Chem Biol. 2009;3(2):138–145
- Altered expression of the Ca(2+)-binding protein S100A1 in human cardiomyopathy. Biochim Biophys Acta. 1996;1313(3):253–257
- Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction. Am J Physiol Heart Circ Physiol. 2009;296(5):H1457–H1465
- Cardiac adenoviral S100A1 gene transfer rescues failing myocardium. J Clin Investig. 2004;114:1550–1563
- Cardiac S100A1 protein levels determine contractile performance and propensity toward heart failure after myocardial infarction. Circulation. 2006;114(12):1258–1268
- . The myocardial protein S100A1 plays a role in the maintenance of normal gene expression in the adult heart. Mol Cell Biochem. 2003;242(1–2):27–33
- Ca(2+)-binding proteins in dogs with heart failure: effects of cardiac contractility modulation electrical signals. Clin Transl Sci. 2009;2(3):211–215
- Retroinfusion-facilitated inotropic AAV9-S100A1 gene therapy restores global cardiac function in a clinically relevant pig heart failure model. Circulation. 2008;118:S_792
- . Transcriptional regulation of S100A1 and expression during mouse heart development. Biochim Biophys Acta. 2000;1498(2–3):207–219
- Ca2+-dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes. Mol Cell Biol. 2007;27(12):4365–4373
- S100A1: a regulator of myocardial contractility. Proc Natl Acad Sci USA. 2001;98(24):13889–13894
- Distinct subcellular location of the Ca2+-binding protein S100A1 differentially modulates Ca2+-cycling in ventricular rat cardiomyocytes. J Cell Sci. 2005;118:421–431
- The small EF-hand Ca2+ binding protein S100A1 increases contractility and Ca2+ cycling in rat cardiac myocytes. Basic Res Cardiol. 2002;97(Suppl.1):I/56–I/62
- S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts. J Gene Med. 2004;6:387–394
- Transgenic overexpression of the Ca2+ binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance. J Biol Chem. 2003;278(5):33809–33817
- S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes. Cell Calcium. 2007;41(2):135–143
- S100A1 prevents arrythmogenic diastolic sarcoplasmic reticulum calcium leak in ventricular cardiomyocytes. Circulation. 2008;118:S_527
- . S100A1 increases the gain of excitation— coupling in isolated rabbit ventricular cardiomyocytes. J Mol Cell Cardiol. 2005;39:900–910
- The C-terminus (aa 75–94) and the linker region (aa 42–54) of the Ca2+ binding protein S100A1 differentially enhance sarcoplasmic Ca2+ release in murine skinned skeletal muscle fibres. J Biol Chem. 2003;278(29):26356–26364
- Interaction of S100A1 with the Ca2+ release channel (ryanodine receptor) of skeletal muscle. Biochemistry. 1997;36(38):11496–11503
- . S100A1 and calmodulin compete for the same binding site on ryanodine receptor. J Biol Chem. 2008;283(39):26676–26683
- Ca(2+)-dependent interaction of S100A1 with the sarcoplasmic reticulum Ca(2+)-ATPase2a and phospholamban in the human heart. Biochem Biophys Res Commun. 2003;306(2):550–557
- The three-dimensional solution structure of Ca2+-bound S100A1 as determined by NMR spectroscopy. J Mol Biol. 2005;353:410–426
- Titin–actin interaction in mouse myocardium: passive tension modulation and its regulation by calcium/s100a1. Biophys J. 2001;81(4):2297–2313
- . Titin-isoform dependence of titin–actin interaction and its regulation by S100A1/Ca2+ in skinned myocardium. J Biomed Biotechnol. 2010;2010:727239 [published online].
- . Cardiac titin: a multifunctional giant. Circulation. 2010;121(19):2137–2145
- . Ultrastructural distribution of the S100A1 Ca2+-binding protein in the human heart. Physiol Res. 2001;50:567–574
- S100A1 modulates Ca2+ sensitivity of cardiac myofilaments. Eur Heart J. 2000;21:60;Suppl.
- . Immunocytochemical localization of S100A1 in mitochondria on cryosections of the rat heart. Gen Physiol Biophys. 2007;26(2):143–149
- S100A1 deficiency results in prolonged ventricular repolarization in response to sympathetic activation. Gen Physiol Biophys. 2008;27(2):127–142
- Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice. Mol Cell Biol. 2002;22(8):2821–2829
- . Ca(2+) signaling in mouse cardiomyocytes with ablated S100A1 protein. Gen Physiol Biophys. 2009;28(4):371–383
- Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue. Circulation. 2007;115(19):2506–2515
- S100A1 gene transfer in myocardium. Eur J Med Res. 2006;11(10):418–422
- S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction. Mol Ther. 2005;12:1120–1129
- Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 2008;118(11):1202–1211
- . Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circ Heart Fail. 2009;2(3):262–271
- . Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6. Nat Med. 2010;16:662–664
PII: S0022-2828(10)00299-3
doi: 10.1016/j.yjmcc.2010.08.012
© 2010 Elsevier Ltd. All rights reserved.
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Journal of Molecular and Cellular Cardiology
Volume 50, Issue 5
, Pages 777-784
, May 2011
