« Previous
Next »
Journal of Molecular and Cellular Cardiology
Volume 48, Issue 6
, Pages 1194-1205
, June 2010
Cardiomyocyte-targeted overexpression of the coxsackie–adenovirus receptor causes a cardiomyopathy in association with β-catenin signaling
References
- . CAR: a virus receptor within the tight junction. Adv Drug Deliv Rev. 2005;57:869–882
- Human coxsackie–adenovirus receptor is colocalized with integrins alpha(v)beta(3) and alpha(v)beta(5) on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections. Circulation. 2001;104:275–280
- . Adenovirus fiber disrupts CAR-mediated intercelllular adhesion allowing virus escape. Cell. 2002;110:789–799
- . The coxsackie virus and adenovirus receptor is a transmembrane component of the tight junction. Proc Natl Acad Sci U S A. 2001;98:15191–15196
- Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5. Science. 1997;275:1320–1323
- . HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci U S A. 1997;94:3352–3356
- The coxsackievirus–adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain. Brain Res Mol Brain Res. 2000;77(1):19–28
- Spatiotemporal changes of coxsackievius and adenovirus receptor in rat hearts during postnatal development and in cultured cardiomyocytes of neonatal rat. Virchows Arch. 2004;444:283–292
- Coxackie and adenovirus receptor is essential for cardiomyocyte development. Genesis. 2005;42:77–85
- Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves. Circ Res. 2006;98:923–930
- Coxsackie–adenovirus receptor (CAR) is essential for early embryonic cardiac development. J Cell Sci. 2005;118:3509–3521
- Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest. 2008;118:2758–2770
- . Coxsackie-and-adenovirus receptor mRNA expression in human heart failure. J Gene Med. 2003;5:876–882
- Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis. Circ Res. 2000;86:275–280
- Induction of coxsackievirus–adenovirus-receptor expression during myocardial tissue formation and remodeling. Identification of a cell-to-cell contact-dependent regulatory mechanism. Circulation. 2003;107:876–882
- The tight junction protein CAR regulates cardiac conduction and cell–cell communication. J Exp Med. 2009;205(10):2369–2379
- Inducible activation of c-Myc in adult myocardium in vivo provokes cardiac myocyte hypertrophy and reactivation of DNA synthesis. Circ Res. 2001;89:1122–1129
- Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death. J Clin Investig. 2002;109:735–743
- . Conditional and targeted overexpression of vascular chymase causes hypertension in transgenic mice. Proc Natl Acad Sci U S A. 2001;98(13):7469–7474
- The coxsackie–adenovirus receptor (CAR) is used by reference strains and clinical isolates representing all six serotypes of coxsackievirus group B and by swine vesicular disease virus. Virology. 2000;271:99–108
- . Conditional transgene expression in the heart. Circ Res. 1996;79:691–697
- Conditional expression of a dominant-negative c-Myb in vascular smooth muscle cells inhibits arterial remodeling after injury. Circ Res. 2003;92:314–321
- Susceptibility to myocarditis is dependent on the response of alpha beta T lymphocytes to coxsackieviral infection. Circ Res. 1999;85:551–558
- Enhanced ERK1/2 activation in mice susceptible to coxsackievirus-induced myocarditis. J Clin Invest. 2002;109:1561–1569
- . Comprehensive mapping of receptor-functioning domains in feline leukemia virus subgroup C receptor FLVCR1. J Virol. 2006;80(4):1742–1751
- Stablilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proc Natl Acad Sci U S A. 2003;100(8):4610–4615
- . A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29(2):2002–2007
- . A comprehensive collection of experimentally validated primers for polymerase chain reaction quantitation of murine transcript abundance. BMC Genomics. 2008;9:633
- . A PCR primer bank for quantitative gene expression analysis. Nucleic Acids Res. 2003;31(24):e154;[1–8]
- Isoform-specific expression of the coxsackie and adenovirus receptor (CAR) in neuromuscular junction and cardiac intercalated discs. BMC Cell Biol. 2004;5:1–8
- The coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX). J Biol Chem. 2003;278:7439–7444
- . CAR is a cell–cell adhesion protein in human cancer cells and is espressionally modulated by dexamethasone, TNFα and TGFβ. Gene Ther. 2003;10:198–205
- . Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer. J Virol. 2000;74(13):6050–6057
- . Can 1000 reviews be wrong? Actin, alpha-catenin, and adherens junctions. Cell. 2005;123:769–772
- . Decisions, decisions: β-catenin chooses between adhesion and transcription. Trends Cell Biol. 2005;15(5):234–237
- . Activation of β-catenin signaling pathways by classical G-protein coupled receptors. Cell Cycle. 2006;5(20):2295–2300
- . Wnt and β-catenin signalling: diseases and therapies. Nat Rev Genet. 2004;5:689–699
- . Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis. Br J Pharmacol. 2008;153:S137–S153
- Phosphorylation of β-catenin by AKT promotes b-catenin transcriptional activity. J Biol Chem. 2007;282(15):11221–11229
- The {beta}-catenin/T-cell factor/lymphocyte enhancer factor signaling pathway is required for normal and stress-induced cardiac hypertrophy. Mol Biol Cell. 2006;26(12):4462–4473
- β-catenin downregulation is reqeuired for adaptive cardiac remodeling. Circ Res. 2007;100:1353–1362
- Upregulation of {gamma}-catenin compensates for the loss of beta-catenin in adult cardiomyocytes. Am J Physiol Heart Circ Physiol. 2007;292(1):H270–H276
- Hypertrophic growth in cardiac myocytes is mediated by myc through a cyclin D2-dependent pathway. EMBO J. 2006;25:3869–3879
- An essential role of Bmp4 in the atrioventricular sepatation of the mouse heart. Genes Dev. 2003;17:2362–2367
- . Developmental signaling in myocardial progenitor cells: a comprehensive view of Bmp- and Wnt/β-catenin signaling. Pediatr Cardiol. 2009;30:609–616
- . A retroviral oncogene, akt, encoding a serine–threonine kinase containing an SH2-like region. Science. 1991;254:274–277
- . Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta. J Biol Chem. 1997;272:30491–30497
- . Akt1 in the cardiovascular system: firend or foe?. J Clin Invest. 2005;115(8):2059–2064
- . Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival. Cell Cycle. 2003;220–223
- Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc Natl Acad Sci U S A. 2002;99:12333–12338
- Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy. J Mol Cell Cardiol. 2005;38:375–385
- Akt/protein kinase B promotes organ growth in transgenic mice. Mol Biol Cell. 2002;22:2799–2809
- . Remodeling the intercalated disc leads to cardiomyopathy in mice misexpressing cadherins in the heart. J Cell Sci. 2002;115:1623–1634
- . Dilated cardiomyopathy: a disease of the intercalated disc?. Trends Cardiovasc Med. 2003;13:30–38
- Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ Res. 2005;96:346–354
PII: S0022-2828(10)00036-2
doi: 10.1016/j.yjmcc.2010.01.022
© 2010 Elsevier Ltd. All rights reserved.
« Previous
Next »
Journal of Molecular and Cellular Cardiology
Volume 48, Issue 6
, Pages 1194-1205
, June 2010
