Journal of Molecular and Cellular Cardiology
Volume 44, Issue 3 , Pages 551-560, March 2008

Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy

  • Jianjian Shi

      Affiliations

    • Herman B Wells Center for Pediatric Research, Division of Pediatric Cardiology, Department of Pediatrics, Indiana University, School of Medicine, Indianapolis, IN, USA
  • ,
  • Yi-Wei Zhang

      Affiliations

    • Herman B Wells Center for Pediatric Research, Division of Pediatric Cardiology, Department of Pediatrics, Indiana University, School of Medicine, Indianapolis, IN, USA
    • Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, PR China
  • ,
  • Lelia J. Summers

      Affiliations

    • Herman B Wells Center for Pediatric Research, Division of Pediatric Cardiology, Department of Pediatrics, Indiana University, School of Medicine, Indianapolis, IN, USA
  • ,
  • Gerald W. Dorn II

      Affiliations

    • Center for Molecular Cardiovascular Research, University of Cincinnati, Cincinnati, OH, USA
  • ,
  • Lei Wei

      Affiliations

    • Herman B Wells Center for Pediatric Research, Division of Pediatric Cardiology, Department of Pediatrics, Indiana University, School of Medicine, Indianapolis, IN, USA
    • Department of Cellular and Integrative Physiology, Indiana University, School of Medicine, Indianapolis, IN, USA
    • Corresponding Author InformationCorresponding author. The Herman B. Wells Center for Pediatric Research, Department of Pediatrics, Indiana University, School of Medicine, R4 building, Room 370, 1044 West Walnut Street, Indianapolis, IN 46202-5225, USA. Tel.: +1 317 274 7894; fax: +1 317 278 9298.

Received 27 August 2007; received in revised form 19 October 2007; accepted 29 November 2007.

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PII: S0022-2828(07)01322-3

doi:10.1016/j.yjmcc.2007.11.018

Journal of Molecular and Cellular Cardiology
Volume 44, Issue 3 , Pages 551-560, March 2008