Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 168-176 , August 2007

Simvastatin inhibits TNFα-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms

  • Neil A. Turner

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Parvinder K. Aley

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Kersten T. Hall

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Philip Warburton

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Stacey Galloway

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Lynne Midgley

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • David J. O'Regan

      Affiliations

    • Department of Cardiac Surgery, The Yorkshire Heart Centre, Leeds General Infirmary, Leeds LS1 3EX, UK
  • ,
  • Ian C. Wood

      Affiliations

    • Institute of Membrane and Systems Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Stephen G. Ball

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
  • ,
  • Karen E. Porter

      Affiliations

    • Academic Unit of Cardiovascular Medicine, Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds LS2 9JT, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 113 3434806; fax: +44 113 3434803.

Received 9 February 2007 ,Revised 4 April 2007 ,Accepted 11 May 2007.

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PII: S0022-2828(07)01045-0

doi: 10.1016/j.yjmcc.2007.05.006

Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 168-176 , August 2007