Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 187-196 , August 2007

T75M-KCNJ2 mutation causing Andersen–Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity

  • Yoshinori Tani

      Affiliations

    • Department of Bio-Informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan
    • Department of Cardiovascular Medicine, Okayama Univeristy Graduate, School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Daiji Miura

      Affiliations

    • Department of Cardiovascular Medicine, Okayama Univeristy Graduate, School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Junko Kurokawa

      Affiliations

    • Department of Bio-Informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan
  • ,
  • Kazufumi Nakamura

      Affiliations

    • Department of Cardiovascular Medicine, Okayama Univeristy Graduate, School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Mamoru Ouchida

      Affiliations

    • Department of Molecular Genetics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Kenji Shimizu

      Affiliations

    • Department of Molecular Genetics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Tohru Ohe

      Affiliations

    • Department of Cardiovascular Medicine, Okayama Univeristy Graduate, School of Medicine, Dentistry and Pharmaceutical, Sciences, Okayama, Japan
  • ,
  • Tetsushi Furukawa

      Affiliations

    • Department of Bio-Informational Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 3 5280 8070; fax: +81 3 5280 8071.

Received 30 November 2006 ,Revised 4 April 2007 ,Accepted 4 May 2007.

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PII: S0022-2828(07)01024-3

doi: 10.1016/j.yjmcc.2007.05.005

Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 187-196 , August 2007