Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 197-209 , August 2007

Time dependent changes in cytoplasmic proteins of the right ventricle during prolonged pressure overload

  • Matthijs J. Faber

      Affiliations

    • Erasmus MC-Sophia, Department of Pediatrics, Division of Pediatric Cardiology, Room Sp-2429, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands
    • ,
  • Michiel Dalinghaus

      Affiliations

    • Erasmus MC-Sophia, Department of Pediatrics, Division of Pediatric Cardiology, Room Sp-2429, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 10 4636264.
    • ,
  • Inge M. Lankhuizen

      Affiliations

    • Erasmus MC-Sophia, Department of Pediatrics, Division of Pediatric Cardiology, Room Sp-2429, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands
    • ,
  • Karel Bezstarosti

      Affiliations

    • Department of Biochemistry, Erasmus MC, Rotterdam, The Netherlands
    • ,
  • Adrie J.M. Verhoeven

      Affiliations

    • Department of Biochemistry, Erasmus MC, Rotterdam, The Netherlands
    • ,
  • Dirk J. Duncker

      Affiliations

    • Department of Experimental Cardiology, Erasmus MC, Rotterdam, The Netherlands
    • ,
  • Willem A. Helbing

      Affiliations

    • Erasmus MC-Sophia, Department of Pediatrics, Division of Pediatric Cardiology, Room Sp-2429, Dr. Molewaterplein 60, 3015 GJ, Rotterdam, The Netherlands
    • ,
  • Jos M.J. Lamers

      Affiliations

    • Department of Biochemistry, Erasmus MC, Rotterdam, The Netherlands

Received 27 October 2006 ,Revised 21 April 2007 ,Accepted 2 May 2007.

References 

  1. Wren C, O'Sullivan JJ. Survival with congenital heart disease and need for follow up in adult life. Heart. 2001;85:438–443
  2. Bolger AP, Coats AJ, Gatzoulis MA. Congenital heart disease: the original heart failure syndrome. Eur. Heart J. 2003;24:970–976
  3. Faber MJ, Dalinghaus M, Lankhuizen IM, Bezstarosti K, Dekkers DH, Duncker DJ, et al. Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: correlations with the degree of hypertrophy. Proteomics. 2005;5:2519–2530
  4. Faber MJ, Dalinghaus M, Lankhuizen IM, Steendijk P, Hop WC, Schoemaker RG, et al. Right- and left ventricular function after chronic pulmonary artery banding in rats assessed with biventricular pressure–volume loops. Am. J. Physiol.: Heart Circ. Physiol. 2006;291:H1580–H1586
  5. Suga H, Sagawa K. Instantaneous pressure–volume relationships and their ratio in the excised, supported canine left ventricle. Circ. Res. 1974;35:117–126
  6. Buttrick PM, Kaplan M, Leinwand LA, Scheuer J. Alterations in gene expression in the rat heart after chronic pathological and physiological loads. J. Mol. Cell. Cardiol. 1994;26:61–67
  7. Schwartz K, Boheler KR, de la Bastie D, Lompre AM, Mercadier JJ. Switches in cardiac muscle gene expression as a result of pressure and volume overload. Am. J. Physiol. 1992;262:R364–R369
  8. Feldman AM, Weinberg EO, Ray PE, Lorell BH. Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ. Res. 1993;73:184–192
  9. Charlemagne D, Maixent JM, Preteseille M, Lelievre LG. Ouabain binding sites and (Na+,K+)-ATPase activity in rat cardiac hypertrophy. Expression of the neonatal forms. J. Biol. Chem. 1986;261:185–189
  10. Bishop SP, Altschuld RA. Increased glycolytic metabolism in cardiac hypertrophy and congestive failure. Am. J. Physiol. 1970;218:153–159
  11. Taegtmeyer H, Overturf ML. Effects of moderate hypertension on cardiac function and metabolism in the rabbit. Hypertension. 1988;11:416–426
  12. Massie BM, Schaefer S, Garcia J, McKirnan MD, Schwartz GG, Wisneski JA, et al. Myocardial high-energy phosphate and substrate metabolism in swine with moderate left ventricular hypertrophy. Circulation. 1995;91:1814–1823
  13. Craig SP, Day IN, Thompson RJ, Craig IW. Localisation of neurone-specific enolase (ENO2) to 12p13. Cytogenet. Cell Genet. 1990;54:71–73
  14. Feo S, Oliva D, Barbieri G, Xu WM, Fried M, Giallongo A. The gene for the muscle-specific enolase is on the short arm of human chromosome 17. Genomics. 1990;6:192–194
  15. Keller A, Ott MO, Lamande N, Lucas M, Gros F, Buckingham M, et al. Activation of the gene encoding the glycolytic enzyme beta-enolase during early myogenesis precedes an increased expression during fetal muscle development. Mech. Dev. 1992;38:41–54
  16. Fletcher L, Rider CC, Taylor CB, Adamson ED, Luke BM, Graham CF. Enolase isoenzymes as markers of differentiation in teratocarcinoma cells and normal tissues of mouse. Dev. Biol. 1978;65:462–475
  17. Merkulova T, Lucas M, Jabet C, Lamande N, Rouzeau JD, Gros F, et al. Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins. Biochem. J. 1997;323(Pt 3):791–800
  18. Keller A, Rouzeau JD, Farhadian F, Wisnewsky C, Marotte F, Lamande N. Differential expression of alpha- and beta-enolase genes during rat heart development and hypertrophy. Am. J. Physiol. 1995;269:H1843–H1851
  19. Schott P, Singer SS, Kogler H, Neddermeier D, Leineweber K, Brodde OE, et al. Pressure overload and neurohumoral activation differentially affect the myocardial proteome. Proteomics. 2005;5:1372–1381
  20. Cullingford TE, Wait R, Clerk A, Sugden PH. Effects of oxidative stress on the cardiac myocyte proteome: modifications to peroxiredoxins and small heat shock proteins. J. Mol. Cell. Cardiol. 2006;40:157–172
  21. Guay J, Lambert H, Gingras-Breton G, Lavoie JN, Huot J, Landry J. Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. J. Cell Sci. 1997;110(Pt 3):357–368
  22. Kacimi R, Chentoufi J, Honbo N, Long CS, Karliner JS. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection. Cardiovasc. Res. 2000;46:139–150
  23. Buermans HP, Redout EM, Schiel AE, Musters RJ, Zuidwijk M, Eijk PP, et al. Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure. Physiol. Genomics. 2005;21:314–323
  24. Sabri A, Steinberg SF. Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failure. Mol. Cell. Biochem. 2003;251:97–101
  25. Braun MU, LaRosee P, Schon S, Borst MM, Strasser RH. Differential regulation of cardiac protein kinase C isozyme expression after aortic banding in rat. Cardiovasc. Res. 2002;56:52–63
  26. Braun MU, Szalai P, Strasser RH, Borst MM. Right ventricular hypertrophy and apoptosis after pulmonary artery banding: regulation of PKC isozymes. Cardiovasc. Res. 2003;59:658–667
  27. Maizels ET, Peters CA, Kline M, Cutler RE, Shanmugam M, Hunzicker-Dunn M. Heat-shock protein-25/27 phosphorylation by the delta isoform of protein kinase C. Biochem. J. 1998;332(Pt 3):703–712
  28. Liu J, Tang M, Mestril R, Wang X. Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin–proteasome system in cardiomyocytes. J. Mol. Cell. Cardiol. 2006;40:451–454
  29. Chavez Zobel AT, Loranger A, Marceau N, Theriault JR, Lambert H, Landry J. Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant. Hum. Mol. Genet. 2003;12:1609–1620
  30. Connell P, Ballinger CA, Jiang J, Wu Y, Thompson LJ, Hohfeld J, et al. The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. Nat. Cell. Biol. 2001;3:93–96
  31. Zhang C, Xu Z, He XR, Michael LH, Patterson C. CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice. Am. J. Physiol.: Heart Circ. Physiol. 2005;288:H2836–H2842
  32. Patterson C. Search and destroy: the role of protein quality control in maintaining cardiac function. J. Mol. Cell. Cardiol. 2006;40:438–441
  33. Wagner E, Luche S, Penna L, Chevallet M, Van Dorsselaer A, Leize-Wagner E, et al. A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress. Biochem. J. 2002;366:777–785
  34. Rabilloud T, Heller M, Gasnier F, Luche S, Rey C, Aebersold R, et al. Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site. J. Biol. Chem. 2002;277:19396–19401
  35. Mitsumoto A, Takanezawa Y, Okawa K, Iwamatsu A, Nakagawa Y. Variants of peroxiredoxins expression in response to hydroperoxide stress. Free Radical Biol. Med. 2001;30:625–635
  36. Baty JW, Hampton MB, Winterbourn CC. Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells. Biochem. J. 2005;389:785–795
  37. Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radical Biol. Med. 2005;38:1543–1552
  38. Nagy N, Malik G, Fisher AB, Das DK. Targeted disruption of peroxiredoxin 6 gene renders the heart vulnerable to ischemia reperfusion injury. Am. J. Physiol.: Heart Circ. Physiol. 2006;291:H2636–H2640
  39. Kirshenbaum LA, Hill M, Singal PK. Endogenous antioxidants in isolated hypertrophied cardiac myocytes and hypoxia-reoxygenation injury. J. Mol. Cell. Cardiol. 1995;27:263–272
  40. Wagner KD, Gmehling G, Gunther J, Stauss HM, Mydlak K, Theres H, et al. Contractile function of rat myocardium is less susceptible to hypoxia/reoxygenation after acute infarction. Mol. Cell. Biochem. 2001;228:49–55
  41. McGregor E, Dunn MJ. Proteomics of heart disease. Hum. Mol. Genet. 2003;12(Spec No 2):R135–R144
  42. Faber MJ, Agnetti G, Bezstarosti K, Lankhuizen IM, Dalinghaus M, Guarnieri C, et al. Recent developments in proteomics: implications for the study of cardiac hypertrophy and failure. Cell. Biochem. Biophys. 2006;44:11–29

PII: S0022-2828(07)01023-1

doi: 10.1016/j.yjmcc.2007.05.002

Journal of Molecular and Cellular Cardiology
Volume 43, Issue 2 , Pages 197-209 , August 2007

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